UNCOMBABLE HAIR SYNDROME

Uncombable hair syndrome  is a rare disorder of the hair shaft of the scalp. It is usually characterized by silvery-blond or straw-colored hair that is disorderly; stands out from the scalp; and cannot be combed flat. It may first become apparent from 3 months of age to 12 years of age. The syndrome has been found to be caused by mutations in the genes . These  genes code for proteins that are involved in hair shaft formation.The syndrome appears to be inherited in an autosomal recessive  fashion

 Signs and symptoms of uncombable hair syndrome

Uncombable hair syndrome may first become apparent any time between the ages of 3 months and 12 years. It only affects the scalp hair. The quantity of hair remains normal, but the hair often grows slowly.Over time the hair becomes progressively silvery-blond or straw-colored; dry and disordered (standing out and growing in different directions); and unmanageable to comb flat. In some cases, constant efforts to groom the hair lead to breakage, but increased fragility is not a constant feature of the condition. In later childhood, there is usually a considerable amount of spontaneous improvement.

Uncombable hair syndrome diagnosis

A diagnosis of uncombable hair syndrome  is made by observing the characteristic symptoms of the condition, as well observing the hair shaft under a special microscope. When the individual hair strands are viewed under a microscope, the hair is either triangular or kidney-shaped on cross section, and has a canal-like longitudinal groove along one or two faces.

 Uncombable hair syndrome be treatment

There is no definitive treatment for uncombable hair syndrome, but the condition usually improves or resolves on its own with the onset of puberty. Gentle hair care is generally recommended using conditioners and soft brushes, along with avoiding harsh hair treatments such as permanent waves (perms); chemical relaxants; or excessive brushing and blow drying.Another strategy that has been suggested to improve the appearance of the hair is the use of biotin supplements.

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